Microbial production of ectoine and hydroxyectoine as high-value chemicals
نویسندگان
چکیده
منابع مشابه
Introducing ectoine as compatible solute: biosynthetic pathway, production and applications
Halophilic microorganisms cope with environmental stresses by producing and accumulating compatible solutes. Ectoine is one of the most important members of compatible solutes which have extra protective properties compared to other compatible solutes. Ectoine attracts several scientific and commercial attention because of their multiple industrial applications. This brief review presents appli...
متن کاملEctD-mediated biotransformation of the chemical chaperone ectoine into hydroxyectoine and its mechanosensitive channel-independent excretion
BACKGROUND Ectoine and its derivative 5-hydroxyectoine are cytoprotectants widely synthesized by microorganisms as a defense against the detrimental effects of high osmolarity on cellular physiology and growth. Both ectoines possess the ability to preserve the functionality of proteins, macromolecular complexes, and even entire cells, attributes that led to their description as chemical chapero...
متن کاملA specialized aspartokinase enhances the biosynthesis of the osmoprotectants ectoine and hydroxyectoine in Pseudomonas stutzeri A1501.
The compatible solutes ectoine and hydroxyectoine are widely produced by bacteria as protectants against osmotic and temperature stress. l-Aspartate-beta-semialdehyde is used as the precursor molecule for ectoine/hydroxyectoine biosynthesis that is catalyzed by the EctABCD enzymes. l-Aspartate-beta-semialdehyde is a central intermediate in different biosynthetic pathways and is produced from l-...
متن کاملMicrobial biotechnology for producing high volume chemicals
Method for the production of isobutanol http://www.freshpatents.com/Method-for-the-productionof-isobutanol-dt20081106ptan20080274526.php This patent describes a biological process for making isobutanol using recombinant bacteria. Isobutanol can be chemical modified to make a range of fuels and chemicals. Benzene free routes to aromatics http://www.frostchemlab.com/green-Synthesis.htm Fermentati...
متن کاملBiochemical Properties of Ectoine Hydroxylases from Extremophiles and Their Wider Taxonomic Distribution among Microorganisms
Ectoine and hydroxyectoine are well-recognized members of the compatible solutes and are widely employed by microorganisms as osmostress protectants. The EctABC enzymes catalyze the synthesis of ectoine from the precursor L-aspartate-β-semialdehyde. A subgroup of the ectoine producers can convert ectoine into 5-hydroxyectoine through a region-selective and stereospecific hydroxylation reaction....
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Microbial Cell Factories
سال: 2021
ISSN: 1475-2859
DOI: 10.1186/s12934-021-01567-6